The faculty of the Department of Orthopaedic Surgery at Northwestern University Feinberg School of Medicine believe that research plays a critical role in the advancement of care. Learn more about the innovative research projects in each of our medical specialties.
Can Pre-Operative Factors Predict Healthcare OverUtilization Following Spine Surgery?
Evaluating the existing relationship between identified potential factors predicting rates of healthcare utilization and complication associated overutilization costs and quantifying rates of overutilization for each identified predictive factor. (PI: Alpesh A. Patel, MD, FACS)
Can a Novel iPad Application Be Used to Objectively Diagnose and Analyze Cervical Myelopathy?
To use a novel iPad application as an objective tool for the quantitative analysis of cervical myelopathy (PI: Alpesh A. Patel, MD, FACS)
Impact Of Single Vs. Multi-Level Anterior Cervical Discectomy And Fusion (ACDF) On Clinical Outcomes And Hospital-Rated Costs.
Determining if patients undergoing two-level or multi-level ACDFs will experience more adverse clinical outcomes and complications, and have higher hospital-related costs compared to patients undergoing single-level ACDF. (PI: Alpesh A. Patel, MD, FACS)
Does Response Shift Exist in Spinal Surgery Patients As Reported Through PROMIS Questionnaires?
Evaluating whether the inherent biases in patient reported outcomes (PROs) is an essential factor to improving the quality of evidence as well as being able to accurately interpret outcomes after a spinal intervention. (PI: Alpesh A. Patel, MD, FACS)
An Assessment of P-15L Bone Graft in Transforaminal Lumbar Interbody Fusion With Instrumentation.
Evaluating if the P-15L bone graft is not inferior in its effectiveness and safety to local autologous bone (and allograft as extender when necessary) when applied in instrumented TLIF in patients with degenerative disc disease. (PI: Wellington K. Hsu, MD)
The Impact Of Adding A Dedicated Advanced Practice Nurse (APN) To An Established Surgical Home On Post-Operative Outcomes in Total Joint Arthroplasty (TJA).
Evaluating whether the incorporation of an APN as part of the multidisciplinary team has an impact on the post-operative outcomes in a total joint Perioperative Surgical Home (PSH). (PI: David W. Manning, MD)
Predicting Next Day Discharge in Patients Undergoing Total Knee Arthroplasty (TKA).
Determining risk factors associated with a greater than 24 hour length of stay following a TKA as well as develop a risk stratification tool that can be used by clinicians to determine which patients would be candidates for next day discharge. (PI: David W. Manning, MD)
Determining The Clinical Course of Prosthetic Hip Dislocations.
Assessing the clinical course of prosthetic hip dislocations, any subsequent dislocations, response to bracing and need for surgery, and identifying factors that may be useful to predice the clinical course. (PI: David W. Manning, MD)
Randomized Prospective Evaluation of Total Knee Replacement (TKA) Component Alignment Using Manual Vs. Custom Instrumentation.
Evaluating differences in TKA implant alignment in patients whose arthroplasty is performe using manual vs custom instrumentation based on measurements derived from pre-operative CT. (PI: David W. Manning, MD)
Evaluation Of Patellar Resurfacing In Patients Undergoing Total Knee Arthroplasty (TKA): A Parallel Clinical Series Study.
Investigating whether patients undergoing a TKA undergoing medial pivot systems benefit from patellar resurfacing in terms of pain and physical function outcomes. (PI: David W. Manning, MD)
Combined Effect Of Tranexamic Acid And Surgical Drains On Transfusion Rates And Blood Loss Post Total Knee Arthroplasty (TKA).
Evaluating the blood loss and transfusion rate following a TKA with combination use intra-operative administration of TXA and a intraarticular surgical drain. (PI: David W. Manning, MD)
Long Term Efficacy Of The GMK Hinge Prosthesis in Total Knee Arthroplasty (TKA).
Evaluating the outcomes of patients undergoing a primary or revision TKA with a Medacta GMK hinge prosthesis by analyzing the survivorship of the prosthesis as well as intra-operative and post-operative complications. (PI: David W. Manning, MD)
Outcomes Of Compressed Staged Bilateral And Unilateral Total Knee Arthroplasty (TKA).
Compare the incidence of complications after staged bilateral TKA when both surgeries are less than 120 days apart. (PI: David W. Manning, MD)
Tracking Functional Outcomes And Patient Satisfaction With A Wearable Smart Brace Following Total Knee Arthroplasty: A Prospective, Randomized Trial.
Determining if the DJO X4 smart brace device can successfully assess and compare patient pre- and post-operative function following a TKA. Additionally, the study is evaluating patient satisfaction, compliance, and ease of wearing the device as directed for the duration of the study. (PI: Matthew D. Beal, MD)
Which Factors Influence Orthopaedic Residents Decision Making Regarding Postgraduate Plans?
Using a anonymous online survey tool, evaluating the factors that are the most important for resident decision making regarding the pursuit of fellowship training and whether those factors are influenced by number of years spent in training or by their subspecialty of choice. (PI: Matthew D. Beal, MD)
Variations In Orthopaedic Training: What Do Residency Case Logs Tell Us About In-Training Surgical Exposure and Future Treatment of Intertrochanteric Fractures?
Determining whether a trend exists among residencies and whether a trend exists in training towards the use of cephomedullary nails (CMN) over sliding hip screws (SHS) in orthopaedic residency training programs in treating intertrochanteric fractures. (PI: Matthew D. Beal, MD)
A Multicenter, Non-Randomized, Prospective Evaluation of Total Knee Arthroplasty (TKA) with the Medacta GMK Sphere® Knee.
Evaluating the patient's ability to forget the artificial joint in everyday life with the GMK sphere medial pivot total knee replacement and reporting clinical, radiographic, and patient reported outcomes (PROs) of subjected implanted with the Medacta GMK sphere. (PI: Kevin D. Hardt, MD)
Outcomes of Primary Total Hip Arthroplasty (THA) In Octogenarians And Nonagenarians.
Examining post-operative outcomes and complications of primary THA in octogenarians and nonagenarians using the American College of Surgeons (ACS) National Surgical Quality Improvement Project (NSQIP) database. (PI: Kevin D. Hardt, MD)
Periacetabular Osteotomy With and Without Arthroscopic Management of Central Compartment Pathology: A Multicenter Randomized Trial.
Defining the role of concomitant/adjunct hip arthroscopy at the time of PAO for patients with symptomatic hip dysplasia and its effects on early clinical outcomes. (PI: Michael D. Stover, MD)
Understanding The Decision Making Process In Patients Undergoing A Periacetabular Osteotomy (PAO) For Hip Dysplasia.
Determining patient satisfaction with their choice, as well as correlating factors in the decision making process to standardize patient reported outcomes (PROs) measures.(PI: Michael D. Stover, MD)
Randomized-Controlled Trial Of An Orthotic Designed To Equalize Leg Lengths For Patients Using A Controlled Ankle Movement (CAM) Boot.
Determining if using the leg-length evening orthotic device can improve balance and/or decrease the development of pain in the lower back and extremities for patients that are weight-bearing-as-tolerated (WBAT) in a CAM boot. (PI: Anish R. Kadakia, MD)
Evaluation Of Operative Vs. Non-Operative Management Of Achilles Tendon Ruptures Using Computerized Adaptive Testing (CAT).
Determining if there is a difference in patient reported outcomes (PROs) between patients treated operatively and non-operatively for acute Achilles tendon ruptures as well as determine whether patient characteristics such as age, sex, insurance status, education, and required daily activity correlate with these outcomes. (PI: Anish R. Kadakia, MD)
Evaluation Of Functional Outcomes Following Ankle Fractures Using Computerized Adaptive Testing (CAT).
Reporting patient reported outcomes (PROs) following an ankle fractures as well as identifying patient factors, injury factors, and treatment factors that correlate with these PROs. (PI: Anish R. Kadakia, MD)
Evaluation Of Operative Vs. Non-Operative Management Of Common Forefoot Disorders Using Computerized Adaptive Testing (CAT).
Determining if there is a difference in patient reported outcomes (PROs) between patients treated operatively and non-operatively for various forefoot disorders as well as determine whether patient characteristics such as age, sex, insurance status, education, and required daily activity correlate with these outcomes. (PI: Anish R. Kadakia, MD)
Evaluation Of Operative Vs. Non-Operative Management Of Common Midfoot Instability and Arthritis Using Computerized Adaptive Testing (CAT).
Determining if there is a difference in patient reported outcomes (PROs) between patients treated operatively and non-operatively for various midfoot disorders as well as determine whether patient characteristics such as age, sex, insurance status, education, and required daily activity correlate with these outcomes. (PI: Anish R. Kadakia, MD)
Evaluation Of Operative Vs. Non-Operative Management Of Common Hindfoot Disorders Using Computerized Adaptive Testing (CAT).
Determining if there is a difference in patient reported outcomes (PROs) between patients treated operatively and non-operatively for various hindfoot disorders as well as determine whether patient characteristics such as age, sex, insurance status, education, and required daily activity correlate with these outcomes. (PI: Anish R. Kadakia, MD)
Retrospective Outcomes Evaluation Of Patients With Ankle Fractures Presenting With Post-Traumatic Osteochondral Lesions Of The Talus.
Determining the type of malleolar fracture (lateral, medial, posterior, bimalleolar, or trimalleolar) when present with osteochondral lesions of the talus (OLT) significantly influences long-term patient reported outcomes (PROs) and satisfaction rates. (PI: Anish R. Kadakia, MD)
Is The Biologic Augmentation Of Tibiotalocalcaneal Arthrodesis (TTCA) Without Tourniquet Associated With Higher Rates Of Fusion?
Examining the surgical outcomes of a novel method of TTCA using biologic augmentation without tourniquet and ankle-foot orthosis (AFO). (PI: Anish R. Kadakia, MD)
Correlating Rotator Cuff Muscle Fatty Infiltration With Glenoid Morphology In Glenohumeral Osteoarthritis.
Determining the influence of rotator cuff muscle fatty infiltration and/or atrophy (reduced muscle volume) on glenoid morphology as measure utilizing MRI in patients who uderwent total shoulder arthroplasty (TSA) for glenohumeral osteoarthritis. (PI: Matthew D. Saltzman, MD)
Risk Factors For Perioperative And 30-Day Complications After Arthroscopic Shoulder Surgery.
Evaluating the peri-operative and 30-day complications and their relations to the type of anesthesia administered. (PI: Matthew D. Saltzman, MD)
Identifying Risk Factors And Correlation Of Diabetic Disease Burden To Adhesive Capsulitis.
To report diseases and risk factors associated with the diagnosis of adhesive capsulitis, and to correlate total diabetic disease burden with incidence of adhesive capsulitis. (PI: Guido Marra, MD)
Long Term Patient Reported and Radiographic Outcomes Of Isolated Acetabuloplasty For Mixed-Type Femoroacetabular Impingement.
Analyzing long term patient reported outcomes and survivorship (time to re-operation or conversion to total hip arthroplasty), as well as identify clincial and radiographic risk factors for poor outcomes following an isolated acetabuloplasty. (PI: Michael A. Terry, MD)
Comparison Of Single And Double Tendon Harvest Using The Tape Locking Screw (TLS) System And TransFix ACL Reconstruction System.
Comparing the clinical outcomes between single tendon grafts using the TLS method, and the double tendon graft using the TransFix method. (PI: Michael A. Terry, MD)
How Many Opiates Should We Prescribe For Pain In Patients Undergoing Knee Arthroscopies And ACL Reconstructions?
Determining if opiates are required to achieve adequate analgesia and whether opiates are routinely overprescribed after knee arthroscopy and ACL reconstructions in an outpatient setting. (PI: Vehniah K. Tjong, MD)
How Many Opiates Should We Prescribe For Pain In Patients Undergoing Hip Arthroscopies?
Determining if opiates are required to achieve adequate analgesia and whether opiates are routinely overprescribed after hip arthroscopy in an outpatient setting. (PI: Vehniah K. Tjong, MD)
Generalized Joint Hypermobility As A Risk Factor For Injury in NCAA Athletes.
Evaluating a large cohort of current NCAA athletes across a wide variety of sports to determine if the risk of injury, both ligamentous and non-ligamentous, in athletes with generalized joint hypermobility (GJH). (PI: Vehniah K. Tjong, MD)
A Qualitative Assessment of Return-To-Sport Following Ulnar Collateral Ligament (UCL) Reconstruction.
Understanding specific subjective intrinsic and extrinsic motivational factors influencing a patient's decision to return-to-sport after UCL reconstruction. (PI: Vehniah K. Tjong, MD)
A Qualitative Assessment of Return-To-Sport Following Partial Meniscectomy, Meniscal Repair, and Conservative Management For Meniscal Tears In The Knee.
Determining the factors that influence a patient's decision to return-to-sport following a partial meniscectomy or meniscal repair surgery, or following conservative (non-surgical) management. (PI: Vehniah K. Tjong, MD)
A Qualitative Assessment Of Return-To-Sport Following A Shoulder Injury in Overhead Athletes.
Investigating the intrinsic and extrinsic motivational factors influencing a overhead athletes (both collegiate and non-collegiate) decision to return-to-sport following a shoulder injury. (PI: Vehniah K. Tjong, MD)
A Qualitative Assessment Of Return-To-Sport In Male And Female Collison Sport Athletes.
Determining specific subjective intrinsic and extrinsic motivational factord influencing a patient's decision to return to a collison sport after surgical intervention as well as identification of sex-based differences in male vs. female collison sport athletes. (PI: Vehniah K. Tjong, MD)
Return-To-Sport After Non-Operative And Operative Management of Grade 2 Syndesmotic Injuries in NCAA Football Players.
Investigating grade II syndesmosis injuries in NCAA athletes and determine the time to return-to-sport following non-operative and operative management. (PI: Vehniah K. Tjong, MD)
There is dedicated funding for hand surgery research in the Mason Fund. Dr. Michael Mason was one of the founders of hand surgery in the United States. He completed his medical student training at Northwestern in the early part of the last century and went on to become a faculty member.
Recent and current projects include studies on:
- Traumatic ulnar translocation of the carpus
- Weakness of thumb flexion after repair of distal radius fractures
- Surface landmarks and measurements in the treatment of trigger thumb
- Surgical treatment of olecranon bone spurs
- Comparison of radial head implant designs
- Surgical techniques to prevent hyperextension of the finger proximal interphalangeal joint
- Comparison of bone graft harvest sites in the upper extremity
The Center is involved in a wide range of research including biomechanical evaluation of shoulder pathology to outcome research. A focus of research is critical evaluation of kinematics of shoulder and elbow arthroplasty. In addition, we have analyzed orthobiologics and gene therapy. The Center presents its work at national and international meetings on a regular basis and we frequently publish our findings in peer-reviewed journals.