The faculty of the Department of Orthopaedic Surgery at Northwestern University Feinberg School of Medicine believe that research plays a critical role in the advancement of care. Learn more about the innovative research projects in each of our medical specialties.
Can pre-operative factors predict healthcare overutilization following spine surgery?
Evaluating existing relationship between identified potential factors predicting rates of healthcare utilization and complication associated overutilization costs and quantifying rates of overutilization for each identified predictive factor. (PI: Alpesh A. Patel, MD, FACS)
A comparison of patient centered outcome measures to evaluate dysphasia and dysphonia after anterior cervical discectomy and fusion.
Evaluating the validity and reliability of the EAT-10 and VHI-10 in the assessment of dysphagia and dysphonia in patients following anterior cervical spinal surgery compared to the Bazaz score. (PI: Alpesh A. Patel, MD, FACS)
High-resolution magnetization transfer (MT) MRI of the cervical spinal cord in patients with cervical spondylotic myelopathy.
Determining the efficacy of high-resolution magnetization transfer (MT) MRI to confirm directionality and intactness of cervical spinal cord tracts in vivo in the setting of cervical myelopathy and disease-free subjects and whether the MT imaging correlates with clinical symptom severity and course. (PI: Alpesh A. Patel, MD, FACS)
Validation of PROMIS® assessment tools against standardized legacy measures in surgical spine patients.
Accurately assessing and comparing results of PROMIS physical function and pain interference, pain behavior, and pain intensity assessment tools against various standardized legacy measures for spine. (PI: Alpesh A. Patel, MD, FACS)
Rates of prescription drug use before and after spinal fusions and the risks factors associated with prolonged use.
Establishing the use of prescription opiate use before spinal fusions, determining the percentage using prescription opiate use more than 3 months post operatively, and determining the risk factors associated with prolonged use using the Illinois Prescription Program. (PI: Alpesh A. Patel, MD, FACS)
Can a Novel iPad Application be Used to Objectively Diagnose and Analyze Cervical Myelopathy?
To use a novel iPad application as an objective tool for the quantitative analysis of cervical myelopathy (PI: Alpesh A. Patel, MD, FACS)
A single blind, prospective, randomized controlled trial on the effect of local steroid application versus intravenous steroids on dysphagia following anterior cervical discectomy and fusion (ACDF).
Determining if the use of steroids decreases the incidence of dysphasia after anterior cervical discectomy and fusion (ACDF) as well as determining which method of steroid administration is most efficacious (IV versus local application). (PI:Alpesh A. Patel, MD, FACS)
An Assessment of P-15L Bone Graft in Transforaminal Lumbar Interbody Fusion with Instrumentation
Evaluating if the P-15L bone graft is not inferior in its effectiveness and safety to local autologous bone (and allograft as extender when necessary) when applied in instrumented TLIF in patients with degenerative disc disease.(PI: Wellington K. Hsu, MD)
A comparison of pedicle length vs. lateral mass - radiographic analysis of pedicle length vs lateral mass in patients with congenital cervical stenosis. (PI: Wellington K. Hsu, MD)
Analysis of muscle volume in patients with congenital cervical stenosis.
Assessing the cross sectional area and composition of musculature in patients with congenital cervical stenosis. (PI: Wellington K. Hsu, MD)
Analysis of outcomes in professional atheletes that underwent a cervical foraminotomy surgery vs. an ACDF surgery. (PI: Wellington K. Hsu, MD)
Surgical exposures and intraabominal anatomy in lateral lumbar interbody fusion.
Identifying obstacles to ideal surgical exposure in the lateral lumbar interbody fusion (LLIF) procedure. (PI: Wellington K. Hsu, MD)
The viability of short vs. long stems in total hip arthroplasty (THA).
Evaluating the viability of short femoral stems vs. standard-length stems in total hip arthroplasty. (PI: Dr. David Manning, MD)
Stability of the medial pivot total knee prosthesis.
Comparing objective and subjective measures of knee stability following total knee arthroplasty with a medial pivot design vs. a posterior stabilized design (PI: Dr. David Manning, MD)
Predicting post surgical complications in total hip and total knee replacement patients using the ACS risk calculator (NISQIP).
Determining if the risk of complications at our institution is comparable to sites involved in the ACS NISQIP data collection and to construct a custom calculator that uses risk factors to better predict actual risk of complications after a THA or TKA. (PI: David Manning, MD)
Anterior vs. posterior approach in total hip arthroplasty (THA).
To determine post-operative differences in the anterior versus posterior approach in THA. (PI: David Manning, MD)
Validation of PROMIS assessment tools against standardized legacy measures in patients undergoing knee replacement surgery.
Assessing and comparing results of PROMIS assessment tools against various standardized legacy measures for patients undergoing knee replacement. (PI: David Manning, MD)
Randomized prospective evaluation of total knee replacement component alignment using manual vs custom instrumentation.
To determine whether the low-dose, biplanar x-ray imaging (EOS) has the same accuracy as computed axial tomography (CT), to validate low-dose, biplanar x-ray imaging (EOS) as a tool to evaluate 3-dimensional alignment of total knee replacement (TKA) implants, and to evaluate differences in total knee replacement implant alignment in patients whose arthroplasty is performed using manual or custom instrumentation derived from preoperative CT. (PI: David Manning, MD)
Using Point of View Video to Improve Surgical Skill: A Pilot Study.
Assessing the feasibility of using a novel point of view video camera (Google Glass) to improve the surgical skills education of orthopaedic surgery residents. (PI: Matthew Beal, MD)
Validation of PROMIS assessment tools against standardized legacy measures in patients undergoing hip replacement surgery.
Assessing and comparing results of PROMIS assessment tools against various standardized legacy measures for patients undergoing knee replacement. (PI: Michael Stover, MD)
Decision making in patients undergoing a periacetabular osteotomy (PAO) for hip dysplasia.
Understanding the decision making process that patients undertake in considering the PAO surgery in order to gauge patient satisfaction with their choice, and also to correlate factors in the decision making process to standardized patient reported outcome measures.(PI: Michael Stover, MD)
Patient factors associated with time to discharge in a short stay total hip replacement program.
Investigating patient factors (medical comorbidities, patient expectations, social support networks, etc.) that may be associated with time to discharge.(PI: Michael Stover, MD)
Measuring Pre-operative and Post-operative function after Total Joint Arthroplasty using Wearable Technology
To introduce a new outcome measurement tool in total joint arthroplasty in the form of wearable technology, investigate the amount of activity (steps taken, duration of sleep) improvement in patients before and after surgery, and compare the data obtained from the wearable technology with standardized legacy measures. (PI: S. David Stulberg, MD)
Evaluation of operative versus nonoperative management of Achilles tendon ruptures using computerized adaptive testing.
Assessing and comparing results of operative versus nonoperative management in patients with Achilles tendon ruptures (PI: Anish R. Kadakia, MD)
Evaluation of functional outcome following ankle fracture using computerized adaptive testing.
Reporting functional outcomes and identifying factors that are associated with functional outcomes following ankle fractures. (PI: Anish R. Kadakia, MD)
Evaluation of operative versus non-operative management of common forefoot disorders using computerized adaptive testing.
Reporting functional outcomes and to compare nonoperative and operative management strategies in the treatment of common forefoot conditions. (PI: Anish R. Kadakia, MD)
Evaluation of operative versus non-operative management ofcommon hind foot disorders using computerized adaptive testing.
Reporting functional outcomes and comparing nonoperative and operative management strategies in the treatment of common hind foot conditions (PI: Anish R. Kadakia, MD)
Evaluation of operative versus non-operative management of midfoot instability and arthritis using computerized adaptive testing.
Reporting functional outcomes and comparing nonoperative and operative management strategies in the treatment of midfoot arthritis and instability. (PI: Anish R. Kadakia, MD)
Retrospective outcome evaluation of patients with ankle fractures presenting with post-traumatic osteochondral lesions of the talus.
Determining the type of malleolar fracture (lateral, medial, posterior, bimalleolar, or trimalleolar) when present with osteochondral lesion of the talus (OLT) significantly influences long-term patient outcomes and satisfaction rates. (PI: Anish R. Kadakia, MD)
Evaluation of Shoulder Replacement and Reconstructive Surgery.
Assessing the quality of outcomes following shoulder surgery, in addition to determining the survivorship of various shoulder implants, and to identify problems that may arise following shoulder replacement surgery and shoulder reconstructive surgery. (PI:Matthew Saltzman, MD)
Identifying risk factors and correlation of diabetic disease burden to adhesive capsulitis.
To report diseases and risk factors associated with the diagnosis of adhesive capsulitis, and to correlate total diabetic disease burden with incidence of adhesive capsulitis. (PI: Guido Marra, MD)
Assessing the Learning Curve of Arthroscopic Knot Tying Psychomotor Skills Acquisition and Repetition Neglect in Orthopedic Surgery Resident Education
To develop and test a bioskills curriculum to facilitate resident education on how to tie arthroscopic knots, and assess the learning curve of resident education in arthroscopic knot tying (PI: Guido Marra, MD)
Evaluation of cement hypotension syndrome in shoulder arthroplasty performed in the beach chair position
To study the effect of cementing on systemic blood pressure during shoulder arthroplasty in the beach chair position. (PI: Guido Marra, MD)
Assessment of Femoral or Acetabular Chondral Defects in the Hip following Microfracture: Utilization of MR Imaging
To assess the utility of MRI for evaluation of post-operative cartilage growth after femoral or acetabular microfracture surgery, and to assess cartilage growth after femoral or acetabular microfracture surgery. (PI: Michael Terry, MD)
A Qualitative Investigation of Perspectives on Return to Sports following Concussion by Varsity Football Athletes.
Investigating the factors influencing a collegiate football player's decision to return to sport following a concussion injury. (PI: Michael Terry, MD)
Comparison of Single Tendon and Double Tendon Harvest Using the Tape Locking Screw System and TransFix ACL Reconstruction System
Comparing the clinical outcomes between single tendon grafts using the TLS method, and double tendon grafts using the TransFix method in ACL reconstruction.(PI: Michael Terry, MD)
How many opiates should we prescribe for pain in patients under knee arthroscopies, hip arthroscopies, and ACL reconstructions?
Determining if opiates are required to achieve adequate analgesia after knee arthroscopy, hip arthroscopy, and ACL reconstruction in a outpatient setting. (PI: Dr. Vehniah Tjong, MD)
Generalized Joint Hypermobility as a Risk Factor for Injury in NCAA Athletes.
Understanding the risk of injury, both ligamentous and non-ligamentous, in athletes with generalized joint hypermobility (GJH).(PI: Dr. Vehniah Tjong, MD)
A Qualitative Assessment of Return to Sport following Ulnar Collateral Ligament Reconstruction.
Understanding specific subjective intrinsic and extrinsic motivational factors influencing a patient's decision to return to sport after UCL reconstruction.(PI: Dr. Vehniah Tjong, MD)
Validation of PROMIS Computer Adaptive Tests (CATs) against standard legacy measures in patients undergoing Hip Arthroscopy surgery.
Validating the PROMIS CATs for pain intensity, pain interference, and physical function by demonstrating feasibility and value of CAT administration and comparing the results to the VAS, HOS, mHHS, and NAHS.(PI: Dr. Vehniah Tjong, MD)
There is dedicated funding for hand surgery research in the Mason Fund. Dr. Michael Mason was one of the founders of hand surgery in the United States. He completed his medical student training at Northwestern in the early part of the last century and went on to become a faculty member.
Recent and current projects include studies on:
- Traumatic ulnar translocation of the carpus
- Weakness of thumb flexion after repair of distal radius fractures
- Surface landmarks and measurements in the treatment of trigger thumb
- Surgical treatment of olecranon bone spurs
- Comparison of radial head implant designs
- Surgical techniques to prevent hyperextension of the finger proximal interphalangeal joint
- Comparison of bone graft harvest sites in the upper extremity
The Center is involved in a wide range of research including biomechanical evaluation of shoulder pathology to outcome research. A focus of research is critical evaluation of kinematics of shoulder and elbow arthroplasty. In addition, we have analyzed orthobiologics and gene therapy. The Center presents its work at national and international meetings on a regular basis and we frequently publish our findings in peer-reviewed journals.